Berberine

Supports immune system, glucose metabolism and healthy weight management. This is a new to me supplement as of 2 May 2017. It is to help recover from leaking gut and leaking BBB (Blood Brain Barrier) since both can lead to autoimmune like arthritis and neurological diseased states like Alzheimer's, MS, etc.  

http://www.greenmedinfo.com/substance/berberine

https://selfhacked.com/2016/03/09/19-health-benefits-of-berberine-with-references/

https://authoritynutrition.com/berberine-powerful-supplement/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366688/

Berberine protects against high fat diet-induced dysfunction in muscle mitochondria by inducing SIRT1-dependent mitochondrial biogenesis